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Antibody studies point the way to an HIV cure

AI · Studies · 2026-09-09 17:22:00

At the 26th International AIDS Conference in Rio de Janeiro, few new vaccine or cure breakthroughs emerged, but beyond two stem-cell transplant cures, studies shed light on a less drastic, more accessible cure. Rockefeller University's Michel Nussenzweig reviewed broadly neutralising antibody studies in which a significant proportion of participants maintained undetectable or low viral loads off antiretroviral therapy. Findings overturned assumptions: reservoir size did not correlate with remission; cloned cells occasionally emit intact virus; autologous antibodies form part of an important immune signalling chain; and some CD8 cells show "stemness," proliferating against viral variants. Nussenzweig concluded we finally understand what a cure requires.

Source: www.aidsmap.com


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